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Gene: PTGR1 (prostaglandin reductase 1) Homo sapiens
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Symbol: PTGR1
Name: prostaglandin reductase 1
Description: Predicted to have 13-prostaglandin reductase activity; 15-oxoprostaglandin 13-oxidase activity; and 2-alkenal reductase [NAD(P)+] activity. Predicted to be involved in oxidation-reduction process; prostaglandin metabolic process; and response to antineoplastic agent. Localizes to the extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 15-oxoprostaglandin 13-reductase; dithiolethione-inducible gene-1; FLJ99229; leukotriene B4 12-hydroxydehydrogenase; LTB4DH; MGC34943; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; PGR1; PRG-1; ZADH3; zinc binding alcohol dehydrogenase domain containing 3
Orthologs:
Mus musculus (house mouse) : Ptgr1 (prostaglandin reductase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ptgr1 (prostaglandin reductase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptgr1 (prostaglandin reductase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGR1 (prostaglandin reductase 1)
Canis lupus familiaris (dog) : PTGR1 (prostaglandin reductase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptgr1 (prostaglandin reductase 1)
Sus scrofa (pig) : PTGR1 (prostaglandin reductase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389111,549,722 - 111,599,855 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379114,312,002 - 114,362,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369113,365,073 - 113,401,532 (-)NCBINCBI36hg18NCBI36
Build 349111,404,807 - 111,441,266NCBI
Celera984,811,079 - 84,861,206 (-)NCBI
Cytogenetic Map9q31.3NCBI
HuRef983,911,040 - 83,960,627 (-)NCBIHuRef
CHM1_19114,458,441 - 114,508,602 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PTGR1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732819
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.