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Gene: SCNN1G (sodium channel epithelial 1 subunit gamma) Homo sapiens
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Symbol: SCNN1G
Name: sodium channel epithelial 1 subunit gamma
Description: Exhibits WW domain binding activity and ion channel activity. Contributes to ligand-gated sodium channel activity. Involved in multicellular organismal water homeostasis; sodium ion homeostasis; and sodium ion transmembrane transport. Localizes to several cellular components, including the extracellular exosome; nucleoplasm; and sodium channel complex. Implicated in Liddle syndrome; autosomal recessive pseudohypoaldosteronism type 1; bronchiectasis 3; and pseudohypoaldosteronism.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: amiloride-sensitive epithelial sodium channel gamma subunit; amiloride-sensitive sodium channel gamma-subunit; amiloride-sensitive sodium channel subunit gamma; BESC3; ENaC gamma subunit; ENaCg; ENaCgamma; epithelial Na(+) channel subunit gamma; gamma-ENaC; gamma-NaCH; LDLS2; nonvoltage-gated sodium channel 1 subunit gamma; PHA1; SCNEG; sodium channe epithelial 1 gamma subunit; sodium channel epithelial 1 gamma subunit; sodium channel, non voltage gated 1 gamma subunit; sodium channel, non-voltage-gated 1, gamma subunit; sodium channel, nonvoltage-gated 1, gamma
Orthologs:
Mus musculus (house mouse) : Scnn1g (sodium channel, nonvoltage-gated 1 gamma)  MGI  Alliance
Rattus norvegicus (Norway rat) : Scnn1g (sodium channel epithelial 1 subunit gamma)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scnn1g (sodium channel epithelial 1 gamma subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SCNN1G (sodium channel epithelial 1 gamma subunit)
Canis lupus familiaris (dog) : SCNN1G (sodium channel epithelial 1 gamma subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scnn1g (sodium channel epithelial 1 gamma subunit)
Sus scrofa (pig) : SCNN1G (sodium channel epithelial 1 gamma subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381623,182,745 - 23,216,883 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371623,194,040 - 23,228,201 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361623,101,541 - 23,135,701 (+)NCBINCBI36hg18NCBI36
Build 341623,101,540 - 23,135,701NCBI
Celera1621,971,795 - 22,005,983 (+)NCBI
Cytogenetic Map16p12.2NCBI
HuRef1621,283,200 - 21,317,389 (+)NCBIHuRef
CHM1_11624,204,072 - 24,239,947 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
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Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SCNN1G
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732847
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-03
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.