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Gene: PRKCG (protein kinase C gamma) Homo sapiens
Symbol: PRKCG
Name: protein kinase C gamma
CRRD ID: 732858
Description: Exhibits protein serine/threonine/tyrosine kinase activity. Involved in negative regulation of protein metabolic process; phosphorylation; and positive regulation of mismatch repair. Predicted to localize to several cellular components, including cytosol; dendrite; and perinuclear region of cytoplasm. Implicated in spinocerebellar ataxia type 14. Biomarker of middle cerebral artery infarction.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC57564; PKC-gamma; PKCC; PKCG; PKCgamma; PKCI(3); protein kinase C gamma type; SCA14
Mus musculus (house mouse) : Prkcg (protein kinase C, gamma)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prkcg (protein kinase C, gamma)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkcg (protein kinase C gamma)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCG (protein kinase C gamma)
Canis lupus familiaris (dog) : PRKCG (protein kinase C gamma)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkcg (protein kinase C gamma)
Sus scrofa (pig) : PRKCG (protein kinase C gamma)
Chlorocebus sabaeus (African green monkey) : PRKCG (protein kinase C gamma)
Heterocephalus glaber (naked mole-rat) : Prkcg (protein kinase C gamma)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1953,879,190 - 53,907,652 (+)EnsemblGRCh38hg38GRCh38
GRCh381953,882,197 - 53,907,652 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371954,385,467 - 54,410,906 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361959,077,279 - 59,102,713 (+)NCBINCBI36hg18NCBI36
Build 341959,077,278 - 59,102,713NCBI
Celera1951,426,508 - 51,451,938 (+)NCBI
Cytogenetic Map19q13.42NCBI
HuRef1950,704,660 - 50,730,288 (+)NCBIHuRef
CHM1_11954,386,644 - 54,412,682 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PRKCG
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732858
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.