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Gene: GTPBP4 (GTP binding protein 4) Homo sapiens
Symbol: GTPBP4
Name: GTP binding protein 4
Description: Exhibits GTP binding activity and GTPase activity. Involved in several processes, including negative regulation of collagen binding activity; protein stabilization; and regulation of protein modification process. Localizes to the cytosol; nucleus; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chronic renal failure gene protein; CRFG; FLJ10686; FLJ10690; FLJ39774; G protein-binding protein CRFG; GTP-binding protein NGB; NGB; NOG1; nucleolar GTP-binding protein 1
Mus musculus (house mouse) : Gtpbp4 (GTP binding protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gtpbp4 (GTP binding protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gtpbp4 (GTP binding protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GTPBP4 (GTP binding protein 4)
Canis lupus familiaris (dog) : GTPBP4 (GTP binding protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gtpbp4 (GTP binding protein 4)
Sus scrofa (pig) : GTPBP4 (GTP binding protein 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3810988,434 - 1,019,932 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37101,034,349 - 1,063,708 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36101,024,349 - 1,053,708 (+)NCBINCBI36hg18NCBI36
Build 34101,024,348 - 1,053,707NCBI
Celera10984,242 - 1,013,986 (+)NCBI
Cytogenetic Map10p15.3NCBI
HuRef10973,776 - 1,003,177 (+)NCBIHuRef
CHM1_1101,033,522 - 1,062,866 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GTPBP4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732875
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.