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Gene: Bik (BCL2-interacting killer) Mus musculus
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Symbol: Bik
Name: BCL2-interacting killer
Description: Predicted to have BH domain binding activity. Involved in apoptotic mitochondrial changes; male gonad development; and spermatogenesis. Localizes to mitochondrial envelope. Is expressed in heart; liver; lung; metanephros; and testis. Human ortholog(s) of this gene implicated in ataxia telangiectasia; breast cancer; colon cancer; and prostate cancer. Orthologous to human BIK (BCL2 interacting killer); PARTICIPATES IN intrinsic apoptotic pathway; INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: apoptosis inducer NBK; bcl-2-interacting killer; Bcl2-interacting killer-like; bik-like killer protein; Biklk; Blk; Nbk
Orthologs:
Homo sapiens (human) : BIK (BCL2 interacting killer)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bik (BCL2-interacting killer)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bik (BCL2 interacting killer)
Pan paniscus (bonobo/pygmy chimpanzee) : BIK (BCL2 interacting killer)
Canis lupus familiaris (dog) : BIK (BCL2 interacting killer)
Chlorocebus sabaeus (African green monkey) : BIK (BCL2 interacting killer)
Heterocephalus glaber (naked mole-rat) : Bik (BCL2 interacting killer)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1583,526,862 - 83,544,634 (+)EnsemblGRCm38mm10GRCm38
GRCm381583,526,790 - 83,544,635 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371583,357,292 - 83,375,065 (+)NCBIGRCm37mm9NCBIm37
MGSCv361584,321,217 - 84,338,990 (+)NCBImm8
MGSCv361583,354,628 - 83,372,401 (+)NCBImm8
Cytogenetic Map15E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Bik
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732887
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.