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Gene: SH3KBP1 (SH3 domain containing kinase binding protein 1) Homo sapiens
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Symbol: SH3KBP1
Name: SH3 domain containing kinase binding protein 1
Description: This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGMX2; c-Cbl-interacting protein; cbl-interacting protein of 85 kDa; CD2-binding protein 3; CD2BP3; CIN85; GIG10; HSB-1; HSB1; human Src family kinase-binding protein 1; IMD61; MIG18; migration-inducing gene 18; SH3 domain-containing kinase-binding protein 1; SH3-domain kinase binding protein 1; Src family kinase-binding protein 1; src-related kinase binding protein-1
Orthologs:
Mus musculus (house mouse) : Sh3kbp1 (SH3-domain kinase binding protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sh3kbp1 (SH3 domain-containing kinase-binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh3kbp1 (SH3 domain containing kinase binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SH3KBP1 (SH3 domain containing kinase binding protein 1)
Canis lupus familiaris (dog) : SH3KBP1 (SH3 domain containing kinase binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh3kbp1 (SH3 domain containing kinase binding protein 1)
Sus scrofa (pig) : SH3KBP1 (SH3 domain containing kinase binding protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X19,533,965 - 19,887,626 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X19,552,083 - 19,905,744 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X19,463,441 - 19,815,640 (-)NCBINCBI36hg18NCBI36
Build 34X19,313,176 - 19,665,376NCBI
CeleraX23,675,636 - 24,008,177 (-)NCBI
Cytogenetic MapXp22.12NCBI
HuRefX17,300,128 - 17,651,187 (-)NCBIHuRef
CHM1_1X19,582,478 - 19,936,208 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SH3KBP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732890
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.