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Gene: Prkch (protein kinase C, eta) Mus musculus
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Symbol: Prkch
Name: protein kinase C, eta
Description: Exhibits Ral GTPase binding activity. Involved in positive regulation of keratinocyte differentiation and positive regulation of macrophage derived foam cell differentiation. Localizes to cell-cell junction; cytosol; and plasma membrane. Human ortholog(s) of this gene implicated in cerebral infarction. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human PRKCH (protein kinase C eta).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: nPKC-eta; PKC-L; Pkch; protein kinase C eta type
Orthologs:
Homo sapiens (human) : PRKCH (protein kinase C eta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prkch (protein kinase C, eta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkch (protein kinase C eta)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCH (protein kinase C eta)
Canis lupus familiaris (dog) : PRKCH (protein kinase C eta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkch (protein kinase C eta)
Sus scrofa (pig) : PRKCH (protein kinase C eta)
Chlorocebus sabaeus (African green monkey) : PRKCH (protein kinase C eta)
Heterocephalus glaber (naked mole-rat) : Prkch (protein kinase C eta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1273,584,796 - 73,778,185 (+)EnsemblGRCm38mm10GRCm38
GRCm381273,584,796 - 73,778,185 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371274,686,028 - 74,879,172 (+)NCBIGRCm37mm9NCBIm37
MGSCv361274,503,879 - 74,697,023 (+)NCBImm8
Celera1274,692,700 - 74,888,950 (+)NCBICelera
Cytogenetic Map12C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Prkch
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732913
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.