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Gene: Prkch (protein kinase C, eta) Mus musculus
Symbol: Prkch
Name: protein kinase C, eta
Description: Exhibits Ral GTPase binding activity. Involved in positive regulation of keratinocyte differentiation and positive regulation of macrophage derived foam cell differentiation. Localizes to cell-cell junction; cytosol; and plasma membrane. Human ortholog(s) of this gene implicated in cerebral infarction. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human PRKCH (protein kinase C eta).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: nPKC-eta; PKC-L; Pkch; protein kinase C eta type
Homo sapiens (human) : PRKCH (protein kinase C eta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prkch (protein kinase C, eta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkch (protein kinase C eta)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCH (protein kinase C eta)
Canis lupus familiaris (dog) : PRKCH (protein kinase C eta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkch (protein kinase C eta)
Sus scrofa (pig) : PRKCH (protein kinase C eta)
Chlorocebus sabaeus (African green monkey) : PRKCH (protein kinase C eta)
Heterocephalus glaber (naked mole-rat) : Prkch (protein kinase C eta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1273,584,796 - 73,778,185 (+)EnsemblGRCm38mm10GRCm38
GRCm381273,584,796 - 73,778,185 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371274,686,028 - 74,879,172 (+)NCBIGRCm37mm9NCBIm37
MGSCv361274,503,879 - 74,697,023 (+)NCBImm8
Celera1274,692,700 - 74,888,950 (+)NCBICelera
Cytogenetic Map12C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Prkch
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732913
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.