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Gene: CORO1A (coronin 1A) Homo sapiens
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Symbol: CORO1A
Name: coronin 1A
CRRD ID: 732928
Description: Exhibits several functions, including cytoskeletal protein binding activity; protein C-terminus binding activity; and protein homodimerization activity. Involved in several processes, including natural killer cell degranulation; negative regulation of actin nucleation; and phagolysosome assembly. Localizes to several cellular components, including actin cytoskeleton; immunological synapse; and phagocytic cup. Predicted to colocalize with actin cytoskeleton. Implicated in coronin-1A deficiency.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CLABP; clipin-A; CLIPINA; coronin, actin binding protein 1a; coronin, actin binding protein, 1A; coronin, actin-binding protein, 1A; coronin, actin-binding, 1A; coronin-1; coronin-1A; coronin-like protein A; coronin-like protein p57; FLJ41407; HCORO1; IMD8; MGC117380; p57; TACO; tryptophan aspartate-containing coat protein
Orthologs:
Mus musculus (house mouse) : Coro1a (coronin, actin binding protein 1A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Coro1a (coronin 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Coro1a (coronin 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : CORO1A (coronin 1A)
Canis lupus familiaris (dog) : CORO1A (coronin 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Coro1a (coronin 1A)
Sus scrofa (pig) : CORO1A (coronin 1A)
Chlorocebus sabaeus (African green monkey) : CORO1A (coronin 1A)
Heterocephalus glaber (naked mole-rat) : Coro1a (coronin 1A)
more info ...
Related Pseudogenes: LOC606724  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1630,182,827 - 30,189,076 (+)EnsemblGRCh38hg38GRCh38
GRCh381630,183,602 - 30,189,076 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371630,194,731 - 30,200,397 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,102,427 - 30,107,898 (+)NCBINCBI36hg18NCBI36
Build 341630,102,448 - 30,107,898NCBI
Celera1672,594,500 - 72,599,971 (-)NCBI
Cytogenetic Map16p11.2NCBI
HuRef1627,857,375 - 27,863,041 (+)NCBIHuRef
CHM1_11631,409,355 - 31,415,021 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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RNA-SEQ Expression

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Nomenclature History
 
More on CORO1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732928
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.