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Gene: Coro1a (coronin, actin binding protein 1A) Mus musculus
Symbol: Coro1a
Name: coronin, actin binding protein 1A
Description: Exhibits actin filament binding activity and identical protein binding activity. Involved in several processes, including early endosome to recycling endosome transport; nerve growth factor signaling pathway; and regulation of organelle organization. Localizes to several cellular components, including the early endosome; immunological synapse; and stereocilium tip. Colocalizes with the actin cytoskeleton. Used to study severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Human ortholog(s) of this gene implicated in coronin-1A deficiency. Is expressed in several structures, including alimentary system; immune system; male reproductive gland or organ; nervous system; and skeletal muscle. Orthologous to human CORO1A (coronin 1A).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Clabp; clipin-A; coronin 1; coronin 1a; coronin-1A; coronin-like actin binding protein; coronin-like protein A; coronin-like protein p57; Lmb3; p57; TACO; tryptophan aspartate-containing coat protein
Homo sapiens (human) : CORO1A (coronin 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Coro1a (coronin 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Coro1a (coronin 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : CORO1A (coronin 1A)
Canis lupus familiaris (dog) : CORO1A (coronin 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Coro1a (coronin 1A)
Sus scrofa (pig) : CORO1A (coronin 1A)
Chlorocebus sabaeus (African green monkey) : CORO1A (coronin 1A)
Heterocephalus glaber (naked mole-rat) : Coro1a (coronin 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7126,699,773 - 126,707,787 (-)EnsemblGRCm38mm10GRCm38
GRCm387126,699,774 - 126,704,816 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377133,843,288 - 133,848,268 (-)NCBIGRCm37mm9NCBIm37
MGSCv367126,490,922 - 126,495,902 (-)NCBImm8
Celera7126,547,074 - 126,552,116 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Coro1a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732929
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.