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Gene: Coro1a (coronin, actin binding protein 1A) Mus musculus
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Symbol: Coro1a
Name: coronin, actin binding protein 1A
Description: Exhibits actin filament binding activity and identical protein binding activity. Involved in several processes, including early endosome to recycling endosome transport; nerve growth factor signaling pathway; and regulation of organelle organization. Localizes to several cellular components, including the early endosome; immunological synapse; and stereocilium tip. Colocalizes with the actin cytoskeleton. Used to study severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Human ortholog(s) of this gene implicated in coronin-1A deficiency. Is expressed in several structures, including alimentary system; immune system; male reproductive gland or organ; nervous system; and skeletal muscle. Orthologous to human CORO1A (coronin 1A).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Clabp; clipin-A; coronin 1; coronin 1a; coronin-1A; coronin-like actin binding protein; coronin-like protein A; coronin-like protein p57; Lmb3; p57; TACO; tryptophan aspartate-containing coat protein
Orthologs:
Homo sapiens (human) : CORO1A (coronin 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Coro1a (coronin 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Coro1a (coronin 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : CORO1A (coronin 1A)
Canis lupus familiaris (dog) : CORO1A (coronin 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Coro1a (coronin 1A)
Sus scrofa (pig) : CORO1A (coronin 1A)
Chlorocebus sabaeus (African green monkey) : CORO1A (coronin 1A)
Heterocephalus glaber (naked mole-rat) : Coro1a (coronin 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl7126,699,773 - 126,707,787 (-)EnsemblGRCm38mm10GRCm38
GRCm387126,699,774 - 126,704,816 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377133,843,288 - 133,848,268 (-)NCBIGRCm37mm9NCBIm37
MGSCv367126,490,922 - 126,495,902 (-)NCBImm8
Celera7126,547,074 - 126,552,116 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Coro1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732929
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.