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Gene: STK3 (serine/threonine kinase 3) Homo sapiens
Symbol: STK3
Name: serine/threonine kinase 3
Description: Exhibits several functions, including ATP binding activity; identical protein binding activity; and magnesium ion binding activity. Involved in several processes, including hippo signaling; positive regulation of DNA-binding transcription factor activity; and protein stabilization. Localizes to the cytoplasm and protein-containing complex.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ90748; KB-1458E12.1; KRS1; mammalian STE20-like protein kinase 2; MST-2; MST2; serine/threonine kinase 3 (STE20 homolog, yeast); serine/threonine kinase 3 (Ste20, yeast homolog); serine/threonine-protein kinase 3; serine/threonine-protein kinase Krs-1; STE20-like kinase MST2
Mus musculus (house mouse) : Stk3 (serine/threonine kinase 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Stk3 (serine/threonine kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stk3 (serine/threonine kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : STK3 (serine/threonine kinase 3)
Canis lupus familiaris (dog) : STK3 (serine/threonine kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stk3 (serine/threonine kinase 3)
Sus scrofa (pig) : STK3 (serine/threonine kinase 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38898,433,048 - 98,944,329 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37899,466,859 - 99,954,799 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36899,536,037 - 99,907,085 (-)NCBINCBI36hg18NCBI36
Build 34899,536,042 - 99,907,085NCBI
Celera895,652,680 - 96,023,711 (-)NCBI
Cytogenetic Map8q22.2NCBI
HuRef894,670,086 - 95,157,575 (-)NCBIHuRef
CHM1_1899,507,181 - 99,995,466 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on STK3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732933
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.