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Gene: FZD3 (frizzled class receptor 3) Homo sapiens
Symbol: FZD3
Name: frizzled class receptor 3
Description: Exhibits PDZ domain binding activity and Wnt-protein binding activity. Involved in canonical Wnt signaling pathway. Localizes to cytoplasm and plasma membrane. Predicted to colocalize with presynaptic active zone. Implicated in Williams-Beuren syndrome and schizophrenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: frizzled 3, seven transmembrane spanning receptor; frizzled family receptor 3; frizzled homolog 3; frizzled-3; Fz-3; hFz3
Mus musculus (house mouse) : Fzd3 (frizzled class receptor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fzd3 (frizzled class receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fzd3 (frizzled class receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : FZD3 (frizzled class receptor 3)
Canis lupus familiaris (dog) : FZD3 (frizzled class receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fzd3 (frizzled class receptor 3)
Sus scrofa (pig) : FZD3 (frizzled class receptor 3)
Chlorocebus sabaeus (African green monkey) : FZD3 (frizzled class receptor 3)
Heterocephalus glaber (naked mole-rat) : Fzd3 (frizzled class receptor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl828,494,205 - 28,574,267 (+)EnsemblGRCh38hg38GRCh38
GRCh38828,494,212 - 28,574,268 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37828,351,722 - 28,431,785 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36828,407,692 - 28,477,901 (+)NCBINCBI36hg18NCBI36
Build 34828,407,691 - 28,477,878NCBI
Celera827,311,635 - 27,381,797 (+)NCBI
Cytogenetic Map8p21.1NCBI
HuRef826,896,974 - 26,976,914 (+)NCBIHuRef
CHM1_1828,553,619 - 28,633,637 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FZD3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732935
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.