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Gene: ONECUT1 (one cut homeobox 1) Homo sapiens
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Symbol: ONECUT1
Name: one cut homeobox 1
Description: This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hepatocyte nuclear factor 6; hepatocyte nuclear factor 6, alpha; HNF-6; HNF6; HNF6A; one cut domain family member 1; one cut domain, family member 1
Orthologs:
Mus musculus (house mouse) : Onecut1 (one cut domain, family member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Onecut1 (one cut homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Onecut1 (one cut homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ONECUT1 (one cut homeobox 1)
Canis lupus familiaris (dog) : ONECUT1 (one cut homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Onecut1 (one cut homeobox 1)
Sus scrofa (pig) : ONECUT1 (one cut homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381552,755,053 - 52,790,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371553,049,160 - 53,082,209 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361550,836,645 - 50,869,501 (-)NCBINCBI36hg18NCBI36
Build 341550,836,644 - 50,869,501NCBI
Celera1529,944,311 - 29,977,184 (-)NCBI
Cytogenetic Map15q21.3NCBI
HuRef1529,879,668 - 29,912,665 (-)NCBIHuRef
CHM1_11553,167,071 - 53,200,155 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ONECUT1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732947
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.