Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ONECUT1 (one cut homeobox 1) Homo sapiens
Symbol: ONECUT1
Name: one cut homeobox 1
Description: This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hepatocyte nuclear factor 6; hepatocyte nuclear factor 6, alpha; HNF-6; HNF6; HNF6A; one cut domain family member 1; one cut domain, family member 1
Mus musculus (house mouse) : Onecut1 (one cut domain, family member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Onecut1 (one cut homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Onecut1 (one cut homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ONECUT1 (one cut homeobox 1)
Canis lupus familiaris (dog) : ONECUT1 (one cut homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Onecut1 (one cut homeobox 1)
Sus scrofa (pig) : ONECUT1 (one cut homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381552,755,053 - 52,790,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371553,049,160 - 53,082,209 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361550,836,645 - 50,869,501 (-)NCBINCBI36hg18NCBI36
Build 341550,836,644 - 50,869,501NCBI
Celera1529,944,311 - 29,977,184 (-)NCBI
Cytogenetic Map15q21.3NCBI
HuRef1529,879,668 - 29,912,665 (-)NCBIHuRef
CHM1_11553,167,071 - 53,200,155 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ONECUT1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732947
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.