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Gene: Ppib (peptidylprolyl isomerase B) Mus musculus
Symbol: Ppib
Name: peptidylprolyl isomerase B
Description: Predicted to contribute to collagen binding activity. Predicted to be involved in several processes, including positive regulation by host of viral genome replication; positive regulation of growth; and protein refolding. Localizes to the endoplasmic reticulum chaperone complex. Used to study osteogenesis imperfecta type 9. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Is expressed in axial skeleton; cranium; otic capsule; and pancreas tip epithelium. Orthologous to human PPIB (peptidylprolyl isomerase B); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; INTERACTS WITH 3H-1,2-dithiole-3-thione; carbon nanotube; clofibrate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408962; AA553318; AI844835; Cphn-2; Cphn2; cyclophilin B; CyP-20b; CYP-S1; peptidyl-prolyl cis-trans isomerase B; PPIase B; rotamase B; S-cyclophilin; SCYLP
Homo sapiens (human) : PPIB (peptidylprolyl isomerase B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ppib (peptidylprolyl isomerase B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppib (peptidylprolyl isomerase B)
Pan paniscus (bonobo/pygmy chimpanzee) : PPIB (peptidylprolyl isomerase B)
Canis lupus familiaris (dog) : PPIB (peptidylprolyl isomerase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppib (peptidylprolyl isomerase B)
Sus scrofa (pig) : PPIB (peptidylprolyl isomerase B)
Chlorocebus sabaeus (African green monkey) : PPIB (peptidylprolyl isomerase B)
Heterocephalus glaber (naked mole-rat) : Ppib (peptidylprolyl isomerase B)
more info ...
Related Pseudogenes: Gm7588   Ppib-rs1   Ppib-rs2  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl966,060,222 - 66,066,623 (+)Ensembl
GRCm38966,060,169 - 66,066,629 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37965,907,976 - 65,914,436 (+)NCBIGRCm37mm9NCBIm37
MGSCv36965,858,175 - 65,864,635 (+)NCBImm8
Celera963,295,684 - 63,302,172 (+)NCBICelera
Cytogenetic Map9CNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ppib
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732991
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.