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Gene: CCN3 (cellular communication network factor 3) Homo sapiens
Symbol: CCN3
Name: cellular communication network factor 3
Description: Exhibits Notch binding activity and integrin binding activity. Involved in several processes, including ameboidal-type cell migration; endothelial cell-cell adhesion; and regulation of signal transduction. Localizes to cytoplasm; gap junction; and intracellular membrane-bounded organelle. Biomarker of pre-eclampsia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CCN family member 3; IBP-9; IGF-binding protein 9; IGFBP-9; IGFBP9; insulin-like growth factor-binding protein 9; nephro blastoma-overexpressed gene protein homolog; nephroblastoma overexpressed; nephroblastoma-overexpressed gene protein homolog; NOV; NOVh; protein NOV homolog
Mus musculus (house mouse) : Ccn3 (cellular communication network factor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccn3 (cellular communication network factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccn3 (cellular communication network factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CCN3 (cellular communication network factor 3)
Canis lupus familiaris (dog) : CCN3 (cellular communication network factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccn3 (cellular communication network factor 3)
Sus scrofa (pig) : CCN3 (cellular communication network factor 3)
Chlorocebus sabaeus (African green monkey) : CCN3 (cellular communication network factor 3)
Heterocephalus glaber (naked mole-rat) : Ccn3 (cellular communication network factor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8119,416,446 - 119,424,434 (+)EnsemblGRCh38hg38GRCh38
GRCh388119,416,446 - 119,424,434 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378120,428,552 - 120,436,678 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368120,497,882 - 120,505,776 (+)NCBINCBI36hg18NCBI36
Build 348120,497,881 - 120,505,776NCBI
Celera8116,617,968 - 116,626,094 (+)NCBI
Cytogenetic Map8q24.12NCBI
HuRef8115,749,069 - 115,757,195 (+)NCBIHuRef
CHM1_18120,469,559 - 120,477,685 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CCN3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 732996
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.