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Gene: Dnase2a (deoxyribonuclease II alpha) Mus musculus
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Symbol: Dnase2a
Name: deoxyribonuclease II alpha
Description: Exhibits deoxyribonuclease II activity. Involved in DNA catabolic process, endonucleolytic; erythrocyte differentiation; and regulation of immune response. Predicted to localize to lysosome. Used to study rheumatoid arthritis. Is expressed in olfactory epithelium and vibrissa. Orthologous to human DNASE2 (deoxyribonuclease 2, lysosomal); INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acid DNase; deoxyribonuclease-2-alpha; DNase II alpha; Dnase2; lysosomal DNase II
Orthologs:
Homo sapiens (human) : DNASE2 (deoxyribonuclease 2, lysosomal)  HGNC  Alliance
Sus scrofa (pig) : DNASE2 (deoxyribonuclease 2, lysosomal)
Chlorocebus sabaeus (African green monkey) : DNASE2 (deoxyribonuclease 2, lysosomal)
Heterocephalus glaber (naked mole-rat) : Dnase2 (deoxyribonuclease 2, lysosomal)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl884,908,560 - 84,922,915 (+)EnsemblGRCm38mm10GRCm38
GRCm38884,908,755 - 84,911,703 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37887,432,523 - 87,435,360 (+)NCBIGRCm37mm9NCBIm37
MGSCv36887,798,729 - 87,801,566 (+)NCBImm8
Celera889,208,019 - 89,210,856 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dnase2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733013
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.