Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MDH2 (malate dehydrogenase 2) Homo sapiens
Analyze
Symbol: MDH2
Name: malate dehydrogenase 2
Description: Exhibits L-malate dehydrogenase activity. Involved in aerobic respiration; internal protein amino acid acetylation; and malate metabolic process. Localizes to the mitochondrion. Implicated in early infantile epileptic encephalopathy 51.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EIEE51; M-MDH; malate dehydrogenase 2, NAD (mitochondrial); malate dehydrogenase, mitochondrial; MDH; MGC:3559; MOR1; testicular tissue protein Li 120
Orthologs:
Mus musculus (house mouse) : Mdh2 (malate dehydrogenase 2, NAD (mitochondrial))  MGI  Alliance
Rattus norvegicus (Norway rat) : Mdh2 (malate dehydrogenase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mdh2 (malate dehydrogenase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MDH2 (malate dehydrogenase 2)
Canis lupus familiaris (dog) : MDH2 (malate dehydrogenase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdh2 (malate dehydrogenase 2)
Sus scrofa (pig) : MDH2 (malate dehydrogenase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38776,048,106 - 76,067,508 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37775,677,182 - 75,696,826 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,515,329 - 75,533,867 (+)NCBINCBI36hg18NCBI36
Build 34775,322,043 - 75,340,579NCBI
Celera770,545,928 - 70,564,452 (+)NCBI
Cytogenetic Map7q11.23NCBI
HuRef770,763,958 - 70,782,483 (+)NCBIHuRef
CHM1_1775,607,324 - 75,626,796 (+)NCBICHM1_1
CRA_TCAGchr7v2775,010,457 - 75,028,995 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MDH2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733026
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.