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Gene: SLC15A4 (solute carrier family 15 member 4) Homo sapiens
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Symbol: SLC15A4
Name: solute carrier family 15 member 4
CRRD ID: 733038
Description: Exhibits transmembrane transporter activity. Involved in several processes, including dipeptide import across plasma membrane; peptidoglycan transport; and positive regulation of toll-like receptor signaling pathway. Localizes to endolysosome membrane and integral component of lysosomal membrane; INTERACTS WITH (-)-demecolcine; 2-methylcholine; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FP12591; hPHT1; peptide transporter 4; peptide-histidine transporter 4; peptide/histidine transporter; peptide/histidine transporter 1; PHT1; PTR4; solute carrier family 15 (oligopeptide transporter), member 4; solute carrier family 15, member 4
Orthologs:
Mus musculus (house mouse) : Slc15a4 (solute carrier family 15, member 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc15a4 (solute carrier family 15 member 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc15a4 (solute carrier family 15 member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC15A4 (solute carrier family 15 member 4)
Canis lupus familiaris (dog) : SLC15A4 (solute carrier family 15 member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc15a4 (solute carrier family 15 member 4)
Sus scrofa (pig) : SLC15A4 (solute carrier family 15 member 4)
Chlorocebus sabaeus (African green monkey) : SLC15A4 (solute carrier family 15 member 4)
Heterocephalus glaber (naked mole-rat) : Slc15a4 (solute carrier family 15 member 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12128,793,194 - 128,823,958 (-)EnsemblGRCh38hg38GRCh38
GRCh3812128,793,194 - 128,823,966 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712129,277,739 - 129,308,541 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612127,843,713 - 127,874,494 (-)NCBINCBI36hg18NCBI36
Build 3412127,802,644 - 127,833,421NCBI
Celera12128,891,861 - 128,922,740 (-)NCBI
Cytogenetic Map12q24.33NCBI
HuRef12126,263,573 - 126,285,425 (-)NCBIHuRef
CHM1_112129,098,609 - 129,129,417 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC15A4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733038
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.