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Gene: Fgfr3 (fibroblast growth factor receptor 3) Mus musculus
Symbol: Fgfr3
Name: fibroblast growth factor receptor 3
Description: Exhibits fibroblast growth factor-activated receptor activity. Involved in several processes, including animal organ development; neurogenesis; and positive regulation of protein modification process. Localizes to the cytoplasmic side of plasma membrane; lysosome; and perinuclear region of cytoplasm. Used to study Muenke Syndrome; achondroplasia; scoliosis; and thanatophoric dysplasia. Human ortholog(s) of this gene implicated in several diseases, including LADD syndrome; SADDAN; acanthosis nigricans; bone disease (multiple); and camptodactyly-tall stature-scoliosis-hearing loss syndrome. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; sensory organ; and skeleton. Orthologous to human FGFR3 (fibroblast growth factor receptor 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD333; Fgfr-3; Flg-2; FR3; HBGFR; heparin-binding growth factor receptor; Mfr3; sam3
Homo sapiens (human) : FGFR3 (fibroblast growth factor receptor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fgfr3 (fibroblast growth factor receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgfr3 (fibroblast growth factor receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : FGFR3 (fibroblast growth factor receptor 3)
Canis lupus familiaris (dog) : FGFR3 (fibroblast growth factor receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgfr3 (fibroblast growth factor receptor 3)
Sus scrofa (pig) : FGFR3 (fibroblast growth factor receptor 3)
Chlorocebus sabaeus (African green monkey) : FGFR3 (fibroblast growth factor receptor 3)
Heterocephalus glaber (naked mole-rat) : Fgfr3 (fibroblast growth factor receptor 3)
more info ...
Related Pseudogenes: Fgfr3-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl533,721,674 - 33,737,068 (+)EnsemblGRCm38mm10GRCm38
GRCm38533,721,724 - 33,737,068 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37534,064,373 - 34,079,713 (+)NCBIGRCm37mm9NCBIm37
MGSCv36534,038,581 - 34,053,924 (+)NCBImm8
Celera531,197,840 - 31,213,184 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fgfr3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733045
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.