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Gene: Fgfr3 (fibroblast growth factor receptor 3) Mus musculus
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Symbol: Fgfr3
Name: fibroblast growth factor receptor 3
Description: Exhibits fibroblast growth factor-activated receptor activity. Involved in several processes, including animal organ development; neurogenesis; and positive regulation of protein modification process. Localizes to the cytoplasmic side of plasma membrane; lysosome; and perinuclear region of cytoplasm. Used to study Muenke Syndrome; achondroplasia; scoliosis; and thanatophoric dysplasia. Human ortholog(s) of this gene implicated in several diseases, including LADD syndrome; SADDAN; acanthosis nigricans; bone disease (multiple); and camptodactyly-tall stature-scoliosis-hearing loss syndrome. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; sensory organ; and skeleton. Orthologous to human FGFR3 (fibroblast growth factor receptor 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD333; Fgfr-3; Flg-2; FR3; HBGFR; heparin-binding growth factor receptor; Mfr3; sam3
Orthologs:
Homo sapiens (human) : FGFR3 (fibroblast growth factor receptor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fgfr3 (fibroblast growth factor receptor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgfr3 (fibroblast growth factor receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : FGFR3 (fibroblast growth factor receptor 3)
Canis lupus familiaris (dog) : FGFR3 (fibroblast growth factor receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgfr3 (fibroblast growth factor receptor 3)
Sus scrofa (pig) : FGFR3 (fibroblast growth factor receptor 3)
Chlorocebus sabaeus (African green monkey) : FGFR3 (fibroblast growth factor receptor 3)
Heterocephalus glaber (naked mole-rat) : Fgfr3 (fibroblast growth factor receptor 3)
more info ...
Related Pseudogenes: Fgfr3-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl533,721,674 - 33,737,068 (+)EnsemblGRCm38mm10GRCm38
GRCm38533,721,724 - 33,737,068 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37534,064,373 - 34,079,713 (+)NCBIGRCm37mm9NCBIm37
MGSCv36534,038,581 - 34,053,924 (+)NCBImm8
Celera531,197,840 - 31,213,184 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fgfr3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733045
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.