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Gene: SIPA1L1 (signal induced proliferation associated 1 like 1) Homo sapiens
Symbol: SIPA1L1
Name: signal induced proliferation associated 1 like 1
Description: Predicted to have GTPase activator activity and ephrin receptor binding activity. Predicted to be involved in several processes, including actin cytoskeleton reorganization; activation of GTPase activity; and regulation of neuron projection development. Predicted to localize to the dendritic spine and postsynaptic density; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686G1344; E6-targeted protein 1; E6TP1; FLJ37213; H_DJ1140G11.1; high-risk human papilloma viruses E6 oncoproteins targeted protein 1; KIAA0440; signal-induced proliferation-associated 1 like 1; signal-induced proliferation-associated 1-like 1; signal-induced proliferation-associated 1-like protein 1; SIPA1-like protein 1; spa-1 like protein p1294; SPAR1; spine-associated RapGAP 1; WUGSC:H_DJ1140G11.1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381471,320,418 - 71,741,209 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371471,788,108 - 72,207,761 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361471,065,795 - 71,275,875 (+)NCBINCBI36hg18NCBI36
Build 341471,065,794 - 71,275,871NCBI
Celera1452,059,323 - 52,269,351 (+)NCBI
Cytogenetic Map14q24.2NCBI
HuRef1452,162,703 - 52,372,954 (+)NCBIHuRef
CHM1_11471,934,292 - 72,146,120 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SIPA1L1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733053
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.