Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SLC40A1 (solute carrier family 40 member 1) Homo sapiens
Analyze
Symbol: SLC40A1
Name: solute carrier family 40 member 1
Description: Exhibits iron ion transmembrane transporter activity and peptide hormone binding activity. Involved in cellular iron ion homeostasis and iron ion transmembrane transport. Localizes to basolateral plasma membrane; cytosol; and nucleoplasm. Implicated in hemochromatosis type 4.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ferroportin 1; ferroportin-1; FPN1; HFE4; IREG1; iron regulated gene 1; iron-regulated transporter 1; MST079; MSTP079; MTP1; putative ferroportin 1 variant IIIA; putative ferroportin 1 variant IIIB; SLC11A3; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 (iron-regulated transporter), member 1
Orthologs:
Mus musculus (house mouse) : Slc40a1 (solute carrier family 40 (iron-regulated transporter), member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc40a1 (solute carrier family 40 member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc40a1 (solute carrier family 40 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC40A1 (solute carrier family 40 member 1)
Canis lupus familiaris (dog) : SLC40A1 (solute carrier family 40 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc40a1 (solute carrier family 40 member 1)
Sus scrofa (pig) : SLC40A1 (solute carrier family 40 member 1)
Chlorocebus sabaeus (African green monkey) : SLC40A1 (solute carrier family 40 member 1)
Heterocephalus glaber (naked mole-rat) : Slc40a1 (solute carrier family 40 member 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2189,560,579 - 189,583,758 (-)EnsemblGRCh38hg38GRCh38
GRCh382189,560,590 - 189,580,811 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372190,425,316 - 190,448,478 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362190,133,561 - 190,153,858 (-)NCBINCBI36hg18NCBI36
Build 342190,250,823 - 190,271,119NCBI
Celera2184,020,234 - 184,040,455 (-)NCBI
Cytogenetic Map2q32.2NCBI
HuRef2182,284,805 - 182,305,032 (-)NCBIHuRef
CHM1_12190,431,102 - 190,451,326 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC40A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733072
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.