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Gene: NRP1 (neuropilin 1) Homo sapiens
Symbol: NRP1
Name: neuropilin 1
Description: Exhibits GTPase activator activity and vascular endothelial growth factor binding activity. Involved in several processes, including cellular response to hepatocyte growth factor stimulus; positive regulation of cellular component organization; and transmembrane receptor protein tyrosine kinase signaling pathway. Localizes to the cytosol; focal adhesion; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BDCA4; CD304; DKFZp686A03134; DKFZp781F1414; neuropilin; neuropilin-1; NP1; NRP; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R
Mus musculus (house mouse) : Nrp1 (neuropilin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nrp1 (neuropilin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrp1 (neuropilin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NRP1 (neuropilin 1)
Canis lupus familiaris (dog) : NRP1 (neuropilin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrp1 (neuropilin 1)
Sus scrofa (pig) : NRP1 (neuropilin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381033,177,491 - 33,334,905 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371033,466,419 - 33,623,833 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361033,506,432 - 33,663,839 (-)NCBINCBI36hg18NCBI36
Build 341033,506,432 - 33,663,476NCBI
Celera1033,231,763 - 33,389,179 (-)NCBI
Cytogenetic Map10p11.22NCBI
HuRef1033,186,444 - 33,343,500 (-)NCBIHuRef
CHM1_11033,468,091 - 33,625,451 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NRP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733081
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.