Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase) Homo sapiens
Analyze
Symbol: NSF
Name: N-ethylmaleimide sensitive factor, vesicle fusing ATPase
Description: Exhibits PDZ domain binding activity and ionotropic glutamate receptor binding activity. Involved in intracellular protein transport; positive regulation of protein catabolic process; and positive regulation of receptor recycling. Localizes to cytosol and plasma membrane; PARTICIPATES IN vasopressin signaling pathway via receptor type 2; INTERACTS WITH (-)-epigallocatechin 3-gallate; 2-hydroxypropanoic acid; 2-methylcholine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: N-ethylmaleimide sensitive factor; N-ethylmaleimide-sensitive factor; N-ethylmaleimide-sensitive factor-like protein; N-ethylmaleimide-sensitive fusion protein; NEM-sensitive fusion protein; SEC18; SKD2; vesicle-fusing ATPase; vesicular-fusion protein NSF
Orthologs:
Related Pseudogenes: NSFP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1746,590,669 - 46,757,464 (+)EnsemblGRCh38hg38GRCh38
GRCh381746,590,669 - 46,757,464 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371744,668,035 - 44,834,830 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361742,023,354 - 42,190,000 (+)NCBINCBI36hg18NCBI36
Build 341742,023,397 - 42,189,993NCBI
Celera1741,231,619 - 41,284,321 (+)NCBI
Cytogenetic Map17q21.31NCBI
HuRef1740,092,157 - 40,095,514 (+)NCBIHuRef
HuRef1740,144,350 - 40,213,196 (+)NCBIHuRef
CHM1_11744,732,424 - 44,898,954 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NSF
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733160
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.