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Gene: CHRNB2 (cholinergic receptor nicotinic beta 2 subunit) Homo sapiens
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Symbol: CHRNB2
Name: cholinergic receptor nicotinic beta 2 subunit
CRRD ID: 733218
Description: Exhibits acetylcholine binding activity; acetylcholine receptor activity; and acetylcholine-gated cation-selective channel activity. Involved in several processes, including behavioral response to nicotine; learning or memory; and response to hypoxia. Localizes to acetylcholine-gated channel complex. Implicated in autosomal dominant nocturnal frontal lobe epilepsy and autosomal dominant nocturnal frontal lobe epilepsy 3.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acetylcholine receptor, nicotinic, beta 2 (neuronal); beta2 human neuronal nicotinic acetylcholine receptor; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); EFNL3; nAChRB2; neuronal acetylcholine receptor subunit beta-2; neuronal nicotinic acetylcholine receptor beta 2
Orthologs:
Mus musculus (house mouse) : Chrnb2 (cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal))  MGI  Alliance
Rattus norvegicus (Norway rat) : Chrnb2 (cholinergic receptor nicotinic beta 2 subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrnb2 (cholinergic receptor nicotinic beta 2 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNB2 (cholinergic receptor nicotinic beta 2 subunit)
Canis lupus familiaris (dog) : CHRNB2 (cholinergic receptor nicotinic beta 2 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrnb2 (cholinergic receptor nicotinic beta 2 subunit)
Sus scrofa (pig) : CHRNB2 (cholinergic receptor nicotinic beta 2 subunit)
Chlorocebus sabaeus (African green monkey) : CHRNB2 (cholinergic receptor nicotinic beta 2 subunit)
Heterocephalus glaber (naked mole-rat) : Chrnb2 (cholinergic receptor nicotinic beta 2 subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1154,567,778 - 154,580,013 (+)EnsemblGRCh38hg38GRCh38
GRCh381154,567,778 - 154,584,708 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371154,540,257 - 154,552,354 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,806,881 - 152,818,978 (+)NCBINCBI36hg18NCBI36
Build 341151,353,329 - 151,362,156NCBI
Celera1127,611,891 - 127,623,988 (+)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1125,903,718 - 125,915,813 (+)NCBIHuRef
CHM1_11155,936,657 - 155,948,754 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

Comparative Map Data
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RNA-SEQ Expression

Sequence

Nucleotide Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on CHRNB2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733218
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.