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Gene: Birc3 (baculoviral IAP repeat-containing 3) Mus musculus
Symbol: Birc3
Name: baculoviral IAP repeat-containing 3
Description: Predicted to have cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of cellular metabolic process; negative regulation of necroptotic process; and positive regulation of protein polyubiquitination. Predicted to localize to several cellular components, including the cytosol; membrane raft; and nucleoplasm. Is expressed in genitourinary system. Orthologous to human BIRC3 (baculoviral IAP repeat containing 3); PARTICIPATES IN ceramide signaling pathway; FasL mediated signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Api1; Api2; apoptosis inhibitor 1; AW107670; baculoviral IAP repeat-containing 2; baculoviral IAP repeat-containing protein 3; Birc2; C-IAP2; cellular inhibitor of apoptosis 2; cIAP-1; cIAP-2; cIAP1; cIAP2; HIAP2; IAP-1; IAP1; IAP2; inhibitor of apoptosis protein 1; mIAP-1; MIAP1; MIAP2; MIHB; MIHC; RING-type E3 ubiquitin transferase BIRC3; RNF49
Homo sapiens (human) : BIRC3 (baculoviral IAP repeat containing 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Birc3 (baculoviral IAP repeat-containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Birc3 (baculoviral IAP repeat containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BIRC3 (baculoviral IAP repeat containing 3)
Canis lupus familiaris (dog) : BIRC3 (baculoviral IAP repeat containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Birc3 (baculoviral IAP repeat containing 3)
Sus scrofa (pig) : BIRC3 (baculoviral IAP repeat containing 3)
Chlorocebus sabaeus (green monkey) : BIRC3 (baculoviral IAP repeat containing 3)
Heterocephalus glaber (naked mole-rat) : Birc3 (baculoviral IAP repeat containing 3)
more info ...
Related Pseudogenes: Gm7019  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl97,848,699 - 7,873,186 (-)Ensembl
GRCm3897,847,468 - 7,873,205 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3797,848,699 - 7,873,170 (-)NCBIGRCm37mm9NCBIm37
MGSCv3697,849,220 - 7,873,545 (-)NCBImm8
Celera95,240,413 - 5,264,652 (-)NCBICelera
Cytogenetic Map9 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Birc3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733266
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.