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Gene: Birc3 (baculoviral IAP repeat-containing 3) Mus musculus
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Symbol: Birc3
Name: baculoviral IAP repeat-containing 3
Description: Predicted to have cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of cellular metabolic process; negative regulation of necroptotic process; and positive regulation of protein polyubiquitination. Predicted to localize to several cellular components, including the cytosol; membrane raft; and nucleoplasm. Is expressed in genitourinary system. Orthologous to human BIRC3 (baculoviral IAP repeat containing 3); PARTICIPATES IN ceramide signaling pathway; FasL mediated signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Api1; Api2; apoptosis inhibitor 1; AW107670; baculoviral IAP repeat-containing 2; baculoviral IAP repeat-containing protein 3; Birc2; C-IAP2; cellular inhibitor of apoptosis 2; cIAP-1; cIAP-2; cIAP1; cIAP2; HIAP2; IAP-1; IAP1; IAP2; inhibitor of apoptosis protein 1; mIAP-1; MIAP1; MIAP2; MIHB; MIHC; RING-type E3 ubiquitin transferase BIRC3; RNF49
Orthologs:
Homo sapiens (human) : BIRC3 (baculoviral IAP repeat containing 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Birc3 (baculoviral IAP repeat-containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Birc3 (baculoviral IAP repeat containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BIRC3 (baculoviral IAP repeat containing 3)
Canis lupus familiaris (dog) : BIRC3 (baculoviral IAP repeat containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Birc3 (baculoviral IAP repeat containing 3)
Sus scrofa (pig) : BIRC3 (baculoviral IAP repeat containing 3)
Chlorocebus sabaeus (green monkey) : BIRC3 (baculoviral IAP repeat containing 3)
Heterocephalus glaber (naked mole-rat) : Birc3 (baculoviral IAP repeat containing 3)
more info ...
Related Pseudogenes: Gm7019  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl97,848,699 - 7,873,186 (-)Ensembl
GRCm3897,847,468 - 7,873,205 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3797,848,699 - 7,873,170 (-)NCBIGRCm37mm9NCBIm37
MGSCv3697,849,220 - 7,873,545 (-)NCBImm8
Celera95,240,413 - 5,264,652 (-)NCBICelera
Cytogenetic Map9 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Birc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733266
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.