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Gene: RACK1 (receptor for activated C kinase 1) Homo sapiens
Symbol: RACK1
Name: receptor for activated C kinase 1
CRRD ID: 733289
Description: Exhibits several functions, including enzyme binding activity; enzyme regulator activity; and protein domain specific binding activity. Involved in several processes, including positive regulation of hydrolase activity; regulation of cellular protein metabolic process; and regulation of signal transduction. Localizes to several cellular components, including IRE1-RACK1-PP2A complex; midbody; and phagocytic cup; PARTICIPATES IN insulin-like growth factor signaling pathway; syndecan signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-hydroxy-5alpha-androstan-3-one; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cell proliferation-inducing gene 21 protein; Gnb2-rs1; GNB2L1; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; guanine nucleotide binding protein beta polypeptide 2-like 1; guanine nucleotide-binding protein subunit beta-2-like 1; guanine nucleotide-binding protein subunit beta-like protein 12.3; H12.3; HLC-7; human lung cancer oncogene 7 protein; lung cancer oncogene 7; PIG21; proliferation-inducing gene 21; protein homologous to chicken B complex protein, guanine nucleotide binding; receptor of activated protein C kinase 1; receptor of activated protein kinase C 1; small ribosomal subunit protein RACK1
Mus musculus (house mouse) : Rack1 (receptor for activated C kinase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rack1 (receptor for activated C kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rack1 (receptor for activated C kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RACK1 (receptor for activated C kinase 1)
Canis lupus familiaris (dog) : RACK1 (receptor for activated C kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rack1 (receptor for activated C kinase 1)
Sus scrofa (pig) : RACK1 (receptor for activated C kinase 1)
Chlorocebus sabaeus (African green monkey) : RACK1 (receptor for activated C kinase 1)
Heterocephalus glaber (naked mole-rat) : Rack1 (receptor for activated C kinase 1)
more info ...
Related Pseudogenes: AC007363.1   AC095059.2   LOC100422561  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl5181,236,897 - 181,248,096 (-)EnsemblGRCh38hg38GRCh38
GRCh385181,236,897 - 181,243,906 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375180,663,928 - 180,671,209 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365180,596,534 - 180,603,512 (-)NCBINCBI36hg18NCBI36
Build 345180,596,556 - 180,603,502NCBI
Celera5176,291,782 - 176,298,759 (-)NCBI
Cytogenetic Map5q35.3NCBI
HuRef5175,390,873 - 175,397,848 (-)NCBIHuRef
CHM1_15180,096,332 - 180,103,310 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RACK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733289
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.