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Gene: Eif2b1 (eukaryotic translation initiation factor 2B, subunit 1 (alpha)) Mus musculus
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Symbol: Eif2b1
Name: eukaryotic translation initiation factor 2B, subunit 1 (alpha)
Description: Predicted to contribute to guanyl-nucleotide exchange factor activity and translation initiation factor activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; negative regulation of guanyl-nucleotide exchange factor activity; and oligodendrocyte development. Predicted to localize to eukaryotic translation initiation factor 2 complex; eukaryotic translation initiation factor 2B complex; and plasma membrane. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Is expressed in several structures, including cranium; nervous system; physiological umbilical hernia; submandibular gland primordium; and thoracic intervertebral disc. Orthologous to human EIF2B1 (eukaryotic translation initiation factor 2B subunit alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 26kDa; D5Ertd406e; eIF-2B GDP-GTP exchange factor subunit alpha; EIF2B; EIF2BA; eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa); MGC6458; translation initiation factor eIF-2B subunit alpha
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl5124,570,213 - 124,579,131 (-)EnsemblGRCm38mm10GRCm38
GRCm385124,570,214 - 124,579,131 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375125,020,223 - 125,029,066 (-)NCBIGRCm37mm9NCBIm37
MGSCv365124,831,271 - 124,839,665 (-)NCBImm8
Celera5121,646,913 - 121,655,757 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map563.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Eif2b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733322
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.