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Gene: CSNK2A1 (casein kinase 2 alpha 1) Homo sapiens
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Symbol: CSNK2A1
Name: casein kinase 2 alpha 1
Description: Exhibits identical protein binding activity; protein N-terminus binding activity; and protein serine/threonine kinase activity. Involved in several processes, including negative regulation of proteolysis; positive regulation of Wnt signaling pathway; and protein phosphorylation. Localizes to the NuRD complex; Sin3 complex; and protein kinase CK2 complex. Colocalizes with the PcG protein complex. Biomarker of breast cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; casein kinase II subunit alpha; casein kinase ii, alpha 1 polypeptide; CK II alpha; CK II alpha 3; CK2 catalytic subunit alpha; CK2A1; Cka1; Cka2; CKII; CSNK2A3; OCNDS; protein kinase CK2
Orthologs:
Mus musculus (house mouse) : Csnk2a1 (casein kinase 2, alpha 1 polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Csnk2a1 (casein kinase 2 alpha 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csnk2a1 (casein kinase 2 alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CSNK2A1 (casein kinase 2 alpha 1)
Canis lupus familiaris (dog) : CSNK2A1 (casein kinase 2 alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csnk2a1 (casein kinase 2 alpha 1)
Sus scrofa (pig) : CSNK2A1 (casein kinase 2 alpha 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3820472,498 - 543,790 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3720463,338 - 524,482 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3620411,338 - 472,482 (-)NCBINCBI36hg18NCBI36
Build 3420411,337 - 472,482NCBI
Celera20558,168 - 619,315 (-)NCBI
Cytogenetic Map20p13NCBI
HuRef20414,534 - 475,783 (-)NCBIHuRef
CHM1_120463,361 - 524,481 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CSNK2A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733323
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.