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Gene: ST14 (suppression of tumorigenicity 14) Homo sapiens
Symbol: ST14
Name: suppression of tumorigenicity 14
Description: Exhibits serine-type peptidase activity. Involved in keratinocyte differentiation and proteolysis. Predicted to localize to the integral component of plasma membrane. Implicated in autosomal recessive congenital ichthyosis 11. Biomarker of ductal carcinoma in situ; dysgerminoma; granulosa cell tumor; prostate carcinoma in situ; and renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ARCI11; HAI; membrane-type serine protease 1; MT-SP1; MTSP1; prostamin; PRSS14; serine protease 14; serine protease TADG-15; SNC19; suppression of tumorigenicity 14 (colon carcinoma); suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin); suppressor of tumorigenicity 14 protein; TADG15; TMPRSS14; tumor associated differentially expressed gene 15 protein; tumor-associated differentially-expressed gene 15 protein
Mus musculus (house mouse) : St14 (suppression of tumorigenicity 14 (colon carcinoma))  MGI  Alliance
Rattus norvegicus (Norway rat) : St14 (suppression of tumorigenicity 14)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : St14 (suppression of tumorigenicity 14)
Pan paniscus (bonobo/pygmy chimpanzee) : ST14 (suppression of tumorigenicity 14)
Canis lupus familiaris (dog) : ST14 (suppression of tumorigenicity 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : St14 (suppression of tumorigenicity 14)
Sus scrofa (pig) : ST14 (suppression of tumorigenicity 14)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3811130,159,782 - 130,210,362 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711130,029,682 - 130,080,257 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611129,534,892 - 129,585,467 (+)NCBINCBI36hg18NCBI36
Build 3411129,534,932 - 129,585,466NCBI
Celera11127,197,379 - 127,248,136 (+)NCBI
Cytogenetic Map11q24.3NCBI
HuRef11125,980,949 - 126,032,941 (+)NCBIHuRef
CHM1_111129,915,529 - 129,966,064 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ST14
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733374
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.