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Gene: St14 (suppression of tumorigenicity 14 (colon carcinoma)) Mus musculus
Symbol: St14
Name: suppression of tumorigenicity 14 (colon carcinoma)
Description: Exhibits serine-type endopeptidase activity. Involved in epithelial cell morphogenesis involved in placental branching and neural tube closure. Localizes to the extracellular region and extrinsic component of plasma membrane. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; pituitary gland; and sensory organ. Orthologous to human ST14 (suppression of tumorigenicity 14); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Epithin; matriptase; matriptase/MT-SP1; mCAP3; MT-SP1; protease, serine, 14 (epithin); Prss14; serine protease 14; suppressor of tumorigenicity 14 protein homolog; Tmprss14
Homo sapiens (human) : ST14 (suppression of tumorigenicity 14)  HGNC  Alliance
Rattus norvegicus (Norway rat) : St14 (suppression of tumorigenicity 14)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : St14 (suppression of tumorigenicity 14)
Pan paniscus (bonobo/pygmy chimpanzee) : ST14 (suppression of tumorigenicity 14)
Canis lupus familiaris (dog) : ST14 (suppression of tumorigenicity 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : St14 (suppression of tumorigenicity 14)
Sus scrofa (pig) : ST14 (suppression of tumorigenicity 14)
Chlorocebus sabaeus (African green monkey) : ST14 (suppression of tumorigenicity 14)
Heterocephalus glaber (naked mole-rat) : St14 (suppression of tumorigenicity 14)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl931,089,402 - 31,131,853 (-)EnsemblGRCm38mm10GRCm38
GRCm38931,088,590 - 31,131,811 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37930,896,175 - 30,939,384 (-)NCBIGRCm37mm9NCBIm37
MGSCv36930,838,155 - 30,881,364 (-)NCBImm8
Celera928,347,788 - 28,391,153 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map916.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on St14
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733375
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.