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Gene: LAMB2 (laminin subunit beta 2) Homo sapiens
Symbol: LAMB2
Name: laminin subunit beta 2
Description: Predicted to have extracellular matrix structural constituent and integrin binding activity. Predicted to be involved in several processes, including basement membrane assembly; cell migration; and substrate adhesion-dependent cell spreading. Localizes to the laminin-3 complex. Colocalizes with the collagen-containing extracellular matrix. Implicated in Pierson syndrome and nephrotic syndrome type 5.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: laminin B1s chain; laminin S; laminin subunit beta-2; laminin, beta 2; laminin, beta 2 (laminin S); laminin-11 subunit beta; laminin-14 subunit beta; laminin-15 subunit beta; laminin-3 subunit beta; laminin-4 subunit beta; laminin-7 subunit beta; laminin-9 subunit beta; LAMS; NPHS5; S-LAM beta; S-laminin subunit beta
Mus musculus (house mouse) : Lamb2 (laminin, beta 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lamb2 (laminin subunit beta 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lamb2 (laminin subunit beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LAMB2 (laminin subunit beta 2)
Canis lupus familiaris (dog) : LAMB2 (laminin subunit beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lamb2 (laminin subunit beta 2)
Sus scrofa (pig) : LAMB2 (laminin subunit beta 2)
more info ...
Related Pseudogenes: LAMB2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38349,121,114 - 49,133,066 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,158,547 - 49,170,599 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,133,551 - 49,145,603 (-)NCBINCBI36hg18NCBI36
Build 34349,133,551 - 49,145,603NCBI
Celera349,115,499 - 49,127,552 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,217,083 - 49,229,135 (-)NCBIHuRef
CHM1_1349,111,294 - 49,123,346 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LAMB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733412
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.