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Gene: XPNPEP1 (X-prolyl aminopeptidase 1) Homo sapiens
Symbol: XPNPEP1
Name: X-prolyl aminopeptidase 1
Description: Exhibits manganese ion binding activity; metalloaminopeptidase activity; and protein homodimerization activity. Involved in bradykinin catabolic process and proteolysis. Localizes to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aminoacylproline aminopeptidase; aminopeptidase P, cytosolic; APP1; cytosolic aminopeptidase P; SAMP; soluble aminopeptidase P; X-Pro aminopeptidase 1; X-prolyl aminopeptidase (aminopeptidase P) 1, soluble; X-prolyl aminopeptidase (aminopeptidase P)-like; X-prolyl aminopeptidase 1, soluble; xaa-Pro aminopeptidase 1; XPNPEP; XPNPEPL; XPNPEPL1
Mus musculus (house mouse) : Xpnpep1 (X-prolyl aminopeptidase (aminopeptidase P) 1, soluble)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xpnpep1 (X-prolyl aminopeptidase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xpnpep1 (X-prolyl aminopeptidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : XPNPEP1 (X-prolyl aminopeptidase 1)
Canis lupus familiaris (dog) : XPNPEP1 (X-prolyl aminopeptidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xpnpep1 (X-prolyl aminopeptidase 1)
Sus scrofa (pig) : XPNPEP1 (X-prolyl aminopeptidase 1)
Chlorocebus sabaeus (African green monkey) : XPNPEP1 (X-prolyl aminopeptidase 1)
Heterocephalus glaber (naked mole-rat) : Xpnpep1 (X-prolyl aminopeptidase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl10109,864,766 - 109,923,553 (-)EnsemblGRCh38hg38GRCh38
GRCh3810109,864,766 - 109,923,553 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710111,624,524 - 111,683,311 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610111,614,514 - 111,673,192 (-)NCBINCBI36hg18NCBI36
Build 3410111,614,513 - 111,673,192NCBI
Celera10105,356,208 - 105,414,975 (-)NCBI
Cytogenetic Map10q25.1NCBI
HuRef10105,255,598 - 105,314,375 (-)NCBIHuRef
CHM1_110111,906,232 - 111,965,041 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on XPNPEP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733430
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.