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Gene: Il1rn (interleukin 1 receptor antagonist) Mus musculus
Symbol: Il1rn
Name: interleukin 1 receptor antagonist
CRRD ID: 733437
Description: Predicted to have cytokine receptor binding activity. Involved in insulin secretion and lipid metabolic process. Localizes to extracellular region and vesicle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); kidney failure (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to human IL1RN (interleukin 1 receptor antagonist); PARTICIPATES IN interleukin-1 signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: F630041P17Rik; IL; IL-1ra; IL-1RN; IL1 inhibitor; interleukin-1 receptor antagonist protein; IRAP
Homo sapiens (human) : IL1RN (interleukin 1 receptor antagonist)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il1rn (interleukin 1 receptor antagonist)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il1rn (interleukin 1 receptor antagonist)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100991079 (interleukin-1 receptor antagonist protein)
Canis lupus familiaris (dog) : IL1RN (interleukin 1 receptor antagonist)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il1rn (interleukin 1 receptor antagonist)
Sus scrofa (pig) : IL1RN (interleukin 1 receptor antagonist)
Chlorocebus sabaeus (African green monkey) : IL1RN (interleukin 1 receptor antagonist)
Heterocephalus glaber (naked mole-rat) : Il1rn (interleukin 1 receptor antagonist)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39224,226,872 - 24,241,503 (+)NCBI
GRCm38224,336,860 - 24,351,491 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl224,336,853 - 24,351,494 (+)EnsemblGRCm38mm10GRCm38
MGSCv37224,192,380 - 24,207,011 (+)NCBIGRCm37mm9NCBIm37
MGSCv36224,158,869 - 24,173,490 (+)NCBImm8
Celera224,056,294 - 24,070,923 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map216.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Il1rn
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733437
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.