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Gene: MEOX2 (mesenchyme homeobox 2) Homo sapiens
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Symbol: MEOX2
Name: mesenchyme homeobox 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II distal enhancer sequence-specific DNA binding activity; and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in negative regulation of cell migration involved in sprouting angiogenesis and positive regulation of transcription by RNA polymerase II. Localizes to the cytoplasm and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GAX; growth arrest-specific homeo box; growth arrest-specific homeobox; homeobox protein MOX-2; mesenchyme homeo box 2; mesenchyme homeo box 2 (growth arrest-specific homeo box); MOX2
Orthologs:
Mus musculus (house mouse) : Meox2 (mesenchyme homeobox 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Meox2 (mesenchyme homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Meox2 (mesenchyme homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MEOX2 (mesenchyme homeobox 2)
Canis lupus familiaris (dog) : MEOX2 (mesenchyme homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Meox2 (mesenchyme homeobox 2)
Sus scrofa (pig) : MEOX2 (mesenchyme homeobox 2)
Chlorocebus sabaeus (green monkey) : MEOX2 (mesenchyme homeobox 2)
Heterocephalus glaber (naked mole-rat) : Meox2 (mesenchyme homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl715,611,212 - 15,686,683 (-)Ensembl
GRCh38715,611,212 - 15,686,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37715,650,837 - 15,726,308 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36715,617,362 - 15,692,833 (-)NCBINCBI36hg18NCBI36
Build 34715,424,076 - 15,499,534NCBI
Celera715,630,544 - 15,706,034 (-)NCBI
Cytogenetic Map7p21.2NCBI
HuRef715,535,672 - 15,611,245 (-)NCBIHuRef
CHM1_1715,650,236 - 15,725,903 (-)NCBICHM1_1
CRA_TCAGchr7v2715,703,946 - 15,779,448 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MEOX2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733480
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.