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Gene: HNRNPK (heterogeneous nuclear ribonucleoprotein K) Homo sapiens
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Symbol: HNRNPK
Name: heterogeneous nuclear ribonucleoprotein K
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and identical protein binding activity. Involved in several processes, including positive regulation of macromolecule biosynthetic process; positive regulation of receptor-mediated endocytosis; and regulation of low-density lipoprotein particle clearance. Localizes to the catalytic step 2 spliceosome; nuclear chromatin; and nucleoplasm. Biomarker of colorectal cancer and prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AUKS; CSBP; dC-stretch binding protein; FLJ41122; hnRNP K; HNRPK; transformation up-regulated nuclear protein; transformation upregulated nuclear protein; TUNP
Orthologs:
Mus musculus (house mouse) : Hnrnpk (heterogeneous nuclear ribonucleoprotein K)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hnrnpk (heterogeneous nuclear ribonucleoprotein K)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hnrnpk (heterogeneous nuclear ribonucleoprotein K)
Pan paniscus (bonobo/pygmy chimpanzee) : HNRNPK (heterogeneous nuclear ribonucleoprotein K)
Canis lupus familiaris (dog) : HNRNPK (heterogeneous nuclear ribonucleoprotein K)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hnrnpk (heterogeneous nuclear ribonucleoprotein K)
Sus scrofa (pig) : HNRNPK (heterogeneous nuclear ribonucleoprotein K)
more info ...
Related Pseudogenes: HNRNPKP1   HNRNPKP2   HNRNPKP3   HNRNPKP4   HNRNPKP5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38983,968,083 - 83,980,782 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37986,582,998 - 86,595,692 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36985,772,912 - 85,785,339 (-)NCBINCBI36hg18NCBI36
Build 34983,812,645 - 83,824,636NCBI
Celera957,154,011 - 57,166,581 (-)NCBI
Cytogenetic Map9q21.32NCBI
HuRef956,408,631 - 56,421,199 (-)NCBIHuRef
CHM1_1986,729,595 - 86,742,294 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on HNRNPK
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733485
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.