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Gene: HNRNPK (heterogeneous nuclear ribonucleoprotein K) Homo sapiens
Symbol: HNRNPK
Name: heterogeneous nuclear ribonucleoprotein K
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and identical protein binding activity. Involved in several processes, including positive regulation of macromolecule biosynthetic process; positive regulation of receptor-mediated endocytosis; and regulation of low-density lipoprotein particle clearance. Localizes to the catalytic step 2 spliceosome; nuclear chromatin; and nucleoplasm. Biomarker of colorectal cancer and prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AUKS; CSBP; dC-stretch binding protein; FLJ41122; hnRNP K; HNRPK; transformation up-regulated nuclear protein; transformation upregulated nuclear protein; TUNP
Mus musculus (house mouse) : Hnrnpk (heterogeneous nuclear ribonucleoprotein K)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hnrnpk (heterogeneous nuclear ribonucleoprotein K)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hnrnpk (heterogeneous nuclear ribonucleoprotein K)
Pan paniscus (bonobo/pygmy chimpanzee) : HNRNPK (heterogeneous nuclear ribonucleoprotein K)
Canis lupus familiaris (dog) : HNRNPK (heterogeneous nuclear ribonucleoprotein K)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hnrnpk (heterogeneous nuclear ribonucleoprotein K)
Sus scrofa (pig) : HNRNPK (heterogeneous nuclear ribonucleoprotein K)
more info ...
Related Pseudogenes: HNRNPKP1   HNRNPKP2   HNRNPKP3   HNRNPKP4   HNRNPKP5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38983,968,083 - 83,980,782 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37986,582,998 - 86,595,692 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36985,772,912 - 85,785,339 (-)NCBINCBI36hg18NCBI36
Build 34983,812,645 - 83,824,636NCBI
Celera957,154,011 - 57,166,581 (-)NCBI
Cytogenetic Map9q21.32NCBI
HuRef956,408,631 - 56,421,199 (-)NCBIHuRef
CHM1_1986,729,595 - 86,742,294 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on HNRNPK
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733485
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.