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Gene: APLNR (apelin receptor) Homo sapiens
Symbol: APLNR
Name: apelin receptor
Description: Predicted to have apelin receptor activity. Involved in several processes, including positive regulation of angiogenesis; positive regulation of release of sequestered calcium ion into cytosol; and regulation of signal transduction. Localizes to the plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGTRL1; angiotensin II receptor-like 1; angiotensin receptor-like 1; APJ; APJ (apelin) receptor; APJ receptor; APJR; FLJ90771; FLJ96609; G protein-coupled receptor APJ; G-protein coupled receptor APJ; G-protein coupled receptor HG11; HG11; HG11 orphan receptor; MGC45246
Mus musculus (house mouse) : Aplnr (apelin receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aplnr (apelin receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aplnr (apelin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : APLNR (apelin receptor)
Canis lupus familiaris (dog) : APLNR (apelin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aplnr (apelin receptor)
Sus scrofa (pig) : APLNR (apelin receptor)
Chlorocebus sabaeus (African green monkey) : APLNR (apelin receptor)
Heterocephalus glaber (naked mole-rat) : Aplnr (apelin receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1157,233,577 - 57,237,314 (-)EnsemblGRCh38hg38GRCh38
GRCh381157,233,577 - 57,237,453 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371157,001,051 - 57,004,927 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,757,643 - 56,761,489 (-)NCBINCBI36hg18NCBI36
Build 341156,757,629 - 56,761,364NCBI
Celera1154,360,003 - 54,363,879 (-)NCBI
Cytogenetic Map11q12.1NCBI
HuRef1153,349,884 - 53,353,760 (-)NCBIHuRef
CHM1_11156,867,161 - 56,871,037 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on APLNR
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733537
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.