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Gene: REM2 (RRAD and GEM like GTPase 2) Homo sapiens
Symbol: REM2
Name: RRAD and GEM like GTPase 2
Description: Predicted to have GTP binding activity and calcium channel regulator activity. Predicted to be involved in negative regulation of high voltage-gated calcium channel activity and signal transduction. Predicted to localize to the plasma membrane; INTERACTS WITH benzo[a]pyrene diol epoxide I; cisplatin; methotrexate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ38964; GTP-binding protein REM 2; rad and gem related gtp binding protein 2; rad and Gem-like GTP-binding protein 2; Rad and Gem-related 2 (rat homolog); RAS (RAD and GEM)-like GTP binding 2; RAS-like GTP binding 2
Mus musculus (house mouse) : Rem2 (rad and gem related GTP binding protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rem2 (RRAD and GEM like GTPase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rem2 (RRAD and GEM like GTPase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : REM2 (RRAD and GEM like GTPase 2)
Canis lupus familiaris (dog) : REM2 (RRAD and GEM like GTPase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rem2 (RRAD and GEM like GTPase 2)
Sus scrofa (pig) : REM2 (RRAD and GEM like GTPase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1422,883,222 - 22,887,678 (+)Ensembl
GRCh381422,883,165 - 22,887,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371423,352,374 - 23,356,889 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,422,272 - 22,426,729 (+)NCBINCBI36hg18NCBI36
Build 341422,422,280 - 22,426,729NCBI
Celera143,215,328 - 3,219,787 (+)NCBI
Cytogenetic Map14q11.2NCBI
HuRef143,469,552 - 3,474,011 (+)NCBIHuRef
CHM1_11423,351,095 - 23,355,552 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on REM2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733550
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.