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Gene: CENPI (centromere protein I) Homo sapiens
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Symbol: CENPI
Name: centromere protein I
Description: This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13. [provided by RefSeq, Jan 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CENP-I; follicle-stimulating hormone primary response protein; FSH primary response 1; FSH primary response protein 1; FSHPRH1; interphase centromere complex protein 19; leucine-rich primary response protein 1; LRPR1; Mis6
Orthologs:
Mus musculus (house mouse) : Cenpi (centromere protein I)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cenpi (centromere protein I)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cenpi (centromere protein I)
Pan paniscus (bonobo/pygmy chimpanzee) : CENPI (centromere protein I)
Canis lupus familiaris (dog) : CENPI (centromere protein I)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cenpi (centromere protein I)
Sus scrofa (pig) : CENPI (centromere protein I)
more info ...
Related Pseudogenes: CENPIP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X101,098,159 - 101,181,847 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X100,353,178 - 100,418,667 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,241,454 - 100,304,634 (+)NCBINCBI36hg18NCBI36
Build 34X100,160,942 - 100,224,121NCBI
CeleraX100,873,565 - 100,936,744 (+)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX90,157,955 - 90,222,098 (+)NCBIHuRef
CHM1_1X100,246,258 - 100,312,461 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CENPI
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733555
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.