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Gene: NLGN3 (neuroligin 3) Homo sapiens
Symbol: NLGN3
Name: neuroligin 3
Description: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Oct 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ASPGX1; AUTSX1; gliotactin homolog; HNL3; KIAA1480; neuroligin-3
Mus musculus (house mouse) : Nlgn3 (neuroligin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nlgn3 (neuroligin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nlgn3 (neuroligin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NLGN3 (neuroligin 3)
Canis lupus familiaris (dog) : NLGN3 (neuroligin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlgn3 (neuroligin 3)
Sus scrofa (pig) : NLGN3 (neuroligin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X71,144,389 - 71,175,307 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X70,364,681 - 70,391,682 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,281,436 - 70,307,776 (+)NCBINCBI36hg18NCBI36
Build 34X70,147,731 - 70,174,070NCBI
CeleraX70,718,556 - 70,744,930 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX64,183,444 - 64,209,758 (+)NCBIHuRef
CHM1_1X70,257,401 - 70,284,066 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NLGN3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733571
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.