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Gene: Apoe (apolipoprotein E) Mus musculus
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Symbol: Apoe
Name: apolipoprotein E
Description: Exhibits several functions, including cholesterol transfer activity; heparan sulfate proteoglycan binding activity; and phosphatidylcholine-sterol O-acyltransferase activator activity. Involved in several processes, including lipid homeostasis; lipoprotein metabolic process; and plasma lipoprotein particle remodeling. Localizes to the glutamatergic synapse and low-density lipoprotein particle. Predicted to colocalize with the early endosome and microtubule. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); eye disease (multiple); familial hyperlipidemia (multiple); and neurodegenerative disease (multiple). Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver and biliary system; and sensory organ. Orthologous to human APOE (apolipoprotein E).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI255918; apo-E
Orthologs:
Homo sapiens (human) : APOE (apolipoprotein E)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Apoe (apolipoprotein E)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoe (apolipoprotein E)
Pan paniscus (bonobo/pygmy chimpanzee) : APOE (apolipoprotein E)
Canis lupus familiaris (dog) : APOE (apolipoprotein E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoe (apolipoprotein E)
Sus scrofa (pig) : APOE (apolipoprotein E)
Chlorocebus sabaeus (green monkey) : APOE (apolipoprotein E)
Heterocephalus glaber (naked mole-rat) : Apoe (apolipoprotein E)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl719,696,109 - 19,699,188 (-)Ensembl
GRCm38719,696,244 - 19,701,310 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37720,281,593 - 20,284,515 (-)NCBIGRCm37mm9NCBIm37
MGSCv36718,854,794 - 18,857,554 (-)NCBImm8
Celera717,102,329 - 17,105,251 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated