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Gene: H3-3B (H3.3 histone B) Homo sapiens
Symbol: H3-3B
Name: H3.3 histone B
Description: Exhibits RNA polymerase II core promoter sequence-specific DNA binding activity; RNA polymerase II distal enhancer sequence-specific DNA binding activity; and nucleosomal DNA binding activity. Involved in DNA replication-independent nucleosome assembly and positive regulation of cell growth. Localizes to the nuclear chromosome, telomeric region and nuclear nucleosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H3 histone family member 3B; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3-3A; H3.3B; H3F3A; H3F3B; histone H3.3
Mus musculus (house mouse) : H3f3b (H3.3 histone B)  MGI  Alliance
Rattus norvegicus (Norway rat) : H3f3b (H3 histone family member 3B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : H3f3b (H3 histone, family 3B)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100988671 (histone H3.3)
Canis lupus familiaris (dog) : H3-3B (H3.3 histone B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101963257 (histone H3.3)
Sus scrofa (pig) : LOC100521680 (histone H3.3)
Chlorocebus sabaeus (green monkey) : H3F3B (H3 histone, family 3B)
Heterocephalus glaber (naked mole-rat) : LOC101698172 (histone H3.3)
more info ...
Related Pseudogenes: H3P18   H3P20   H3P21   H3P36   H3P41   H3P43  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1775,776,434 - 75,785,893 (-)Ensembl
GRCh381775,776,434 - 75,779,779 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371773,772,515 - 73,775,860 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,284,110 - 71,287,455 (-)NCBINCBI36hg18NCBI36
Build 341771,284,111 - 71,287,455NCBI
Celera1770,362,565 - 70,365,910 (-)NCBI
Cytogenetic Map17q25.1NCBI
HuRef1769,198,034 - 69,201,379 (-)NCBIHuRef
CHM1_11773,837,589 - 73,841,087 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H3-3B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733608
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.