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Gene: GTF2A1 (general transcription factor IIA subunit 1) Homo sapiens
Symbol: GTF2A1
Name: general transcription factor IIA subunit 1
Description: Exhibits several functions, including RNA polymerase II general transcription initiation factor activity; TBP-class protein binding activity; and protein heterodimerization activity. Involved in transcription by RNA polymerase II. Localizes to cytosol; transcription factor TFIIA complex; and transcription factor TFIID complex.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ21525; general transcription factor 2a, 1; general transcription factor IIA 1; general transcription factor IIA, 1, 19/37kDa; glucose regulated protein, 58kD pseudogene; MGC129969; MGC129970; TF2A1; TFIIA; TFIIA alpha, p55, isoform 1; TFIIA alpha/beta subunits; TFIIA-42; TFIIAL; transcription initiation factor IIA subunit 1; transcription initiation factor TFIIA 42 kDa subunit
Mus musculus (house mouse) : Gtf2a1 (general transcription factor II A, 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gtf2a1 (general transcription factor 2A subunit 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gtf2a1 (general transcription factor IIA subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GTF2A1 (general transcription factor IIA subunit 1)
Canis lupus familiaris (dog) : GTF2A1 (general transcription factor IIA subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gtf2a1 (general transcription factor IIA subunit 1)
Sus scrofa (pig) : GTF2A1 (general transcription factor IIA subunit 1)
Chlorocebus sabaeus (African green monkey) : GTF2A1 (general transcription factor IIA subunit 1)
Heterocephalus glaber (naked mole-rat) : Gtf2a1 (general transcription factor IIA subunit 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1481,175,452 - 81,221,377 (-)EnsemblGRCh38hg38GRCh38
GRCh381481,175,452 - 81,221,390 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371481,641,796 - 81,687,575 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361480,716,147 - 80,757,328 (-)NCBINCBI36hg18NCBI36
Build 341480,716,146 - 80,757,328NCBI
Celera1461,686,296 - 61,727,496 (-)NCBI
Cytogenetic Map14q31.1NCBI
HuRef1461,809,402 - 61,855,401 (-)NCBIHuRef
CHM1_11481,582,217 - 81,627,845 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GTF2A1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733620
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.