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Gene: Alox15 (arachidonate 15-lipoxygenase) Mus musculus
Symbol: Alox15
Name: arachidonate 15-lipoxygenase
CRRD ID: 733626
Description: Exhibits arachidonate 12(S)-lipoxygenase activity and arachidonate 15-lipoxygenase activity. Involved in several processes, including icosanoid metabolic process; phosphatidylethanolamine biosynthetic process; and regulation of engulfment of apoptotic cell. Localizes to cytosol and plasma membrane. Is expressed in several structures, including alimentary system; liver; nose; peritoneal fluid; and respiratory system. Orthologous to human ALOX15 (arachidonate 15-lipoxygenase); PARTICIPATES IN atherosclerosis pathway; type 1 diabetes mellitus pathway; acetylsalicylic acid pharmacodynamics pathway; INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; 4,4'-sulfonyldiphenol; 6-oxoprostaglandin F1alpha.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 12-; 12-LO; 12-LOX; 12/15-lipoxygenase; 12/15-LO; 15-LOX; Alo; Alox12l; arachidonate 12-lipoxygenase, leukocyte-type; arachidonate omega-6 lipoxygenase; hepoxilin A3 synthase Alox15; L-1; L-12LO; linoleate 13S-lipoxygenase; polyunsaturated fatty acid lipoxygenase ALOX15
Homo sapiens (human) : ALOX15 (arachidonate 15-lipoxygenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Alox15 (arachidonate 15-lipoxygenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alox15 (arachidonate 15-lipoxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALOX15 (arachidonate 15-lipoxygenase)
Canis lupus familiaris (dog) : ALOX15 (arachidonate 15-lipoxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alox15 (arachidonate 15-lipoxygenase)
Sus scrofa (pig) : ALOX15 (arachidonate 15-lipoxygenase)
Chlorocebus sabaeus (African green monkey) : ALOX15 (arachidonate 15-lipoxygenase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1170,344,152 - 70,352,031 (-)EnsemblGRCm38mm10GRCm38
GRCm381170,344,147 - 70,390,538 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371170,157,649 - 70,165,533 (-)NCBIGRCm37mm9NCBIm37
MGSCv361170,160,348 - 70,168,210 (-)NCBImm8
Celera1177,888,721 - 77,896,673 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Alox15
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733626
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.