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Gene: GATA3 (GATA binding protein 3) Homo sapiens
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Symbol: GATA3
Name: GATA binding protein 3
Description: Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; E-box binding activity; and HMG box domain binding activity. Involved in several processes, including cellular response to cytokine stimulus; regulation of cell motility; and regulation of gene expression. Localizes to nuclear chromatin and nucleoplasm. Implicated in hypoparathyroidism; hypoparathyroidism-deafness-renal disease syndrome; nephrosis; and sensorineural hearing loss. Biomarker of asthma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GATA-binding factor 3; gata-binding protein 3; HDR; HDRS; MGC2346; MGC5199; MGC5445; trans-acting T-cell-specific transcription factor GATA-3
Orthologs:
Mus musculus (house mouse) : Gata3 (GATA binding protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gata3 (GATA binding protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gata3 (GATA binding protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GATA3 (GATA binding protein 3)
Canis lupus familiaris (dog) : GATA3 (GATA binding protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gata3 (GATA binding protein 3)
Sus scrofa (pig) : GATA3 (GATA binding protein 3)
Chlorocebus sabaeus (African green monkey) : GATA3 (GATA binding protein 3)
Heterocephalus glaber (naked mole-rat) : Gata3 (GATA binding protein 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl108,045,378 - 8,075,198 (+)EnsemblGRCh38hg38GRCh38
GRCh38108,045,420 - 8,075,198 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37108,087,294 - 8,117,164 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36108,136,673 - 8,157,170 (+)NCBINCBI36hg18NCBI36
Build 34108,136,672 - 8,157,170NCBI
Celera108,022,059 - 8,042,539 (+)NCBI
Cytogenetic Map10p14NCBI
HuRef108,015,002 - 8,035,471 (+)NCBIHuRef
CHM1_1108,096,969 - 8,117,441 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GATA3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733638
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.