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Gene: Lta (lymphotoxin A) Mus musculus
Symbol: Lta
Name: lymphotoxin A
CRRD ID: 733657
Description: Predicted to have tumor necrosis factor receptor binding activity. Involved in several processes, including lymph node development; positive regulation of immune response; and positive regulation of interferon-gamma production. Predicted to localize to extracellular space. Is expressed in several structures, including extraembryonic component; female reproductive system; hemolymphoid system; intestine; and liver. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); glucose metabolism disease (multiple); leishmaniasis (multiple); and lung disease (multiple). Orthologous to human LTA (lymphotoxin alpha); PARTICIPATES IN interleukin-4 signaling pathway; type 1 diabetes mellitus pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hlb38; hlb382; L; LT; LT-; LT-[; LT-[a]; LT-alpha; LT[; LT[a]; LTalpha; Ltx; lymph; lymphotoxin alpha; lymphotoxin-alpha; MGC117668; Tnf; TNF beta; TNF-be; TNF-beta; Tnfb; Tnfsf; TNFSF1; Tnfsf1b; Tnlg1e; tumor necrosis factor ligand 1e; tumor necrosis factor ligand superfamily member 1
Homo sapiens (human) : LTA (lymphotoxin alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lta (lymphotoxin alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lta (lymphotoxin alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : LTA (lymphotoxin alpha)
Canis lupus familiaris (dog) : LTA (lymphotoxin alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lta (lymphotoxin alpha)
Sus scrofa (pig) : LTA (lymphotoxin alpha)
Heterocephalus glaber (naked mole-rat) : Lta (lymphotoxin alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391735,422,141 - 35,424,568 (-)NCBI
GRCm381735,203,165 - 35,205,578 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,203,165 - 35,205,351 (-)EnsemblGRCm38mm10GRCm38
MGSCv371735,340,110 - 35,342,296 (-)NCBIGRCm37mm9NCBIm37
MGSCv361734,811,215 - 34,813,235 (-)NCBImm8
Celera1738,299,868 - 38,302,049 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lta
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733657
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.