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Gene: Lta (lymphotoxin A) Mus musculus
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Symbol: Lta
Name: lymphotoxin A
CRRD ID: 733657
Description: Predicted to have tumor necrosis factor receptor binding activity. Involved in several processes, including lymph node development; positive regulation of immune response; and positive regulation of interferon-gamma production. Predicted to localize to extracellular space. Is expressed in several structures, including extraembryonic component; female reproductive system; hemolymphoid system; intestine; and liver. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); glucose metabolism disease (multiple); leishmaniasis (multiple); and lung disease (multiple). Orthologous to human LTA (lymphotoxin alpha); PARTICIPATES IN interleukin-4 signaling pathway; type 1 diabetes mellitus pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hlb38; hlb382; L; LT; LT-; LT-[; LT-[a]; LT-alpha; LT[; LT[a]; LTalpha; Ltx; lymph; lymphotoxin alpha; lymphotoxin-alpha; MGC117668; Tnf; TNF beta; TNF-be; TNF-beta; Tnfb; Tnfsf; TNFSF1; Tnfsf1b; Tnlg1e; tumor necrosis factor ligand 1e; tumor necrosis factor ligand superfamily member 1
Orthologs:
Homo sapiens (human) : LTA (lymphotoxin alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lta (lymphotoxin alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lta (lymphotoxin alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : LTA (lymphotoxin alpha)
Canis lupus familiaris (dog) : LTA (lymphotoxin alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lta (lymphotoxin alpha)
Sus scrofa (pig) : LTA (lymphotoxin alpha)
Heterocephalus glaber (naked mole-rat) : Lta (lymphotoxin alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,422,141 - 35,424,568 (-)NCBI
GRCm381735,203,165 - 35,205,578 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,203,165 - 35,205,351 (-)EnsemblGRCm38mm10GRCm38
MGSCv371735,340,110 - 35,342,296 (-)NCBIGRCm37mm9NCBIm37
MGSCv361734,811,215 - 34,813,235 (-)NCBImm8
Celera1738,299,868 - 38,302,049 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lta
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733657
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.