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Gene: PSME2 (proteasome activator subunit 2) Homo sapiens
Symbol: PSME2
Name: proteasome activator subunit 2
Description: Exhibits identical protein binding activity. Predicted to be involved in positive regulation of endopeptidase activity; regulation of G1/S transition of mitotic cell cycle; and regulation of proteasomal protein catabolic process. Localizes to the extracellular exosome and membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 11S regulator complex beta subunit; 11S regulator complex subunit beta; activator of multicatalytic protease subunit 2; cell migration-inducing protein 22; MCP activator, 31-kD subunit; PA28B; PA28beta; protease (prosome, macropain) 28 subunit, beta; proteasome (prosome, macropain) activator subunit 2 (PA28 beta); proteasome activator 28 subunit beta; proteasome activator 28-beta; proteasome activator complex subunit 2; proteasome activator hPA28 subunit beta; REG-beta; REGbeta
Mus musculus (house mouse) : Psme2 (proteasome (prosome, macropain) activator subunit 2 (PA28 beta))  MGI  Alliance
Rattus norvegicus (Norway rat) : Psme2 (proteasome activator subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psme2 (proteasome activator subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PSME2 (proteasome activator subunit 2)
Canis lupus familiaris (dog) : PSME2 (proteasome activator subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psme2 (proteasome activator subunit 2)
Sus scrofa (pig) : PSME2 (proteasome activator subunit 2)
more info ...
Related Pseudogenes: PSME2P1   PSME2P2   PSME2P3   PSME2P4   PSME2P5   PSME2P6  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1424,143,362 - 24,147,570 (-)Ensembl
GRCh381424,143,365 - 24,146,646 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371424,612,574 - 24,615,855 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,682,414 - 23,685,695 (-)NCBINCBI36hg18NCBI36
Build 341423,682,413 - 23,685,695NCBI
Celera144,477,042 - 4,480,323 (-)NCBI
Cytogenetic Map14q12NCBI
HuRef144,727,638 - 4,730,919 (-)NCBIHuRef
CHM1_11424,611,243 - 24,614,524 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PSME2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733724
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.