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Gene: ADCY8 (adenylate cyclase 8) Homo sapiens
Symbol: ADCY8
Name: adenylate cyclase 8
Description: Predicted to have several functions, including calcium- and calmodulin-responsive adenylate cyclase activity; calmodulin binding activity; and protein dimerization activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to organonitrogen compound; and regulation of synaptic plasticity. Predicted to colocalize with actin cytoskeleton.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AC8; ADCY3; adenylate cyclase 8 (brain); adenylate cyclase type 8; adenylate cyclase type VIII; adenylyl cyclase 8; adenylyl cyclase-8, brain; ATP pyrophosphate-lyase 8; ca(2+)/calmodulin-activated adenylyl cyclase; epididymis secretory sperm binding protein Li 172mP; HBAC1; HEL-S-172mP
Mus musculus (house mouse) : Adcy8 (adenylate cyclase 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adcy8 (adenylate cyclase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adcy8 (adenylate cyclase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ADCY8 (adenylate cyclase 8)
Canis lupus familiaris (dog) : ADCY8 (adenylate cyclase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcy8 (adenylate cyclase 8)
Sus scrofa (pig) : ADCY8 (adenylate cyclase 8)
Chlorocebus sabaeus (African green monkey) : ADCY8 (adenylate cyclase 8)
Heterocephalus glaber (naked mole-rat) : Adcy8 (adenylate cyclase 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8130,780,301 - 131,040,909 (-)EnsemblGRCh38hg38GRCh38
GRCh388130,780,300 - 131,041,604 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378131,792,546 - 132,053,012 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368131,861,729 - 132,123,854 (-)NCBINCBI36hg18NCBI36
Build 348131,861,728 - 132,123,854NCBI
Celera8127,969,937 - 128,230,969 (-)NCBI
Cytogenetic Map8q24.22NCBI
HuRef8127,112,105 - 127,216,470 (-)NCBIHuRef
HuRef8127,235,506 - 127,372,263 (-)NCBIHuRef
CHM1_18131,833,662 - 132,093,872 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ADCY8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733733
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.