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Gene: Prdx1 (peroxiredoxin 1) Mus musculus
Symbol: Prdx1
Name: peroxiredoxin 1
Description: Exhibits identical protein binding activity. Involved in several processes, including natural killer cell mediated cytotoxicity; regulation of intracellular signal transduction; and removal of superoxide radicals. Localizes to the mitochondrion and myelin sheath. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Is expressed in several structures, including alimentary system; central nervous system; metanephros; respiratory system; and sensory organ. Orthologous to human PRDX1 (peroxiredoxin 1); INTERACTS WITH 2,3,7,8-tetrabromodibenzodioxine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene.
Type: protein-coding
Also known as: macrophage 23 Kd stress protein; macrophage 23 kDa stress protein; macrophage 23kDa stress protein; macrophase stress protein 22kDa; macrophase stress protein 23 kd; MSP23; NkefA; OSF-3; OSF3; osteoblast specific factor 3; osteoblast-specific factor 3; PAG; Paga; peroxiredoxin-1; PrdxI; proliferation-associated gene A; prx1; PrxI; Tdpx2; TDX2; thioredoxin dependent peroxide reductase 2; thioredoxin peroxidase 2; thioredoxin-dependent peroxide reductase 2; TPxA; Trx dependent peroxide reductase 2
Homo sapiens (human) : PRDX1 (peroxiredoxin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prdx1 (peroxiredoxin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prdx1 (peroxiredoxin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PRDX1 (peroxiredoxin 1)
Canis lupus familiaris (dog) : PRDX1 (peroxiredoxin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prdx1 (peroxiredoxin 1)
Sus scrofa (pig) : PRDX1 (peroxiredoxin 1)
more info ...
Related Pseudogenes: Gm17915   Gm21399   Gm7204   Prdx1-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl4116,685,544 - 116,700,822 (+)Ensembl
GRCm384116,685,599 - 116,700,000 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374116,358,204 - 116,372,605 (+)NCBIGRCm37mm9NCBIm37
MGSCv364116,183,531 - 116,197,932 (+)NCBImm8
Celera4115,419,593 - 115,433,994 (+)NCBICelera
Cytogenetic Map4 D1NCBI
cM Map453.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Prdx1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733745
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.