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Gene: ROCK1 (Rho associated coiled-coil containing protein kinase 1) Homo sapiens
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Symbol: ROCK1
Name: Rho associated coiled-coil containing protein kinase 1
Description: Exhibits Rho-dependent protein serine/threonine kinase activity and aspartic-type endopeptidase inhibitor activity. Involved in several processes, including intracellular signal transduction; regulation of epithelial cell differentiation; and regulation of protein metabolic process. Colocalizes with the amyloid-beta complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC131603; MGC43611; p160 ROCK-1; p160-ROCK; P160ROCK; PRO0435; renal carcinoma antigen NY-REN-35; Rho kinase; rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase I; ROCK-I
Orthologs:
Related Pseudogenes: ROCK1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1820,946,906 - 21,111,813 (-)EnsemblGRCh38hg38GRCh38
GRCh381820,946,906 - 21,111,813 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371818,529,701 - 18,691,812 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361816,783,699 - 16,945,810 (-)NCBINCBI36hg18NCBI36
Build 341816,787,532 - 16,944,869NCBI
Celera1815,335,539 - 15,497,459 (-)NCBI
Cytogenetic Map18q11.1NCBI
HuRef1815,376,598 - 15,538,887 (-)NCBIHuRef
CHM1_11818,456,721 - 18,618,879 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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RNA-SEQ Expression

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Nucleotide Sequences
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Additional Information

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Nomenclature History
 
More on ROCK1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733751
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.