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Gene: Lss (lanosterol synthase) Mus musculus
Symbol: Lss
Name: lanosterol synthase
Description: Predicted to have lanosterol synthase activity. Predicted to be involved in cholesterol biosynthetic process and regulation of protein stability. Predicted to localize to the intracellular membrane-bounded organelle and lipid droplet. Human ortholog(s) of this gene implicated in cataract 44 and hypotrichosis 14. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human LSS (lanosterol synthase).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2,3-epoxysqualene--lanosterol cyclase; 2810025N20Rik; BC029082; D10Ertd116e; MGC27893; Osc; oxidosqualene--lanosterol cyclase
Homo sapiens (human) : LSS (lanosterol synthase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lss (lanosterol synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lss (lanosterol synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : LSS (lanosterol synthase)
Canis lupus familiaris (dog) : LSS (lanosterol synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lss (lanosterol synthase)
Sus scrofa (pig) : LSS (lanosterol synthase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1076,531,588 - 76,557,138 (+)Ensembl
GRCm381076,531,565 - 76,557,139 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371075,994,372 - 76,016,679 (+)NCBIGRCm37mm9NCBIm37
MGSCv361075,975,343 - 75,997,650 (+)NCBImm8
Celera1077,576,142 - 77,598,449 (+)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1039.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lss
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733768
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.