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Gene: SLC6A3 (solute carrier family 6 member 3) Homo sapiens
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Symbol: SLC6A3
Name: solute carrier family 6 member 3
Description: Exhibits dopamine:sodium symporter activity. Involved in dopamine uptake. Localizes to several cellular components, including the cell surface; flotillin complex; and neuronal cell body. Implicated in attention deficit hyperactivity disorder; nicotine dependence; and obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DA transporter; DAT; DAT1; dopamine transporter 1; PKDYS; PKDYS1; sodium-dependent dopamine transporter; solute carrier family 6 (neurotransmitter transporter), member 3; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; solute carrier family 6, member 3
Orthologs:
Mus musculus (house mouse) : Slc6a3 (solute carrier family 6 (neurotransmitter transporter, dopamine), member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc6a3 (solute carrier family 6 member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc6a3 (solute carrier family 6 member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC6A3 (solute carrier family 6 member 3)
Canis lupus familiaris (dog) : SLC6A3 (solute carrier family 6 member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc6a3 (solute carrier family 6 member 3)
Sus scrofa (pig) : SLC6A3 (solute carrier family 6 member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl51,392,794 - 1,445,440 (-)Ensembl
GRCh3851,392,794 - 1,445,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3751,392,905 - 1,445,543 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3651,445,909 - 1,498,538 (-)NCBINCBI36hg18NCBI36
Build 3451,445,908 - 1,498,543NCBI
Celera51,429,610 - 1,484,220 (-)NCBI
Cytogenetic Map5p15.33NCBI
HuRef51,373,680 - 1,426,892 (-)NCBIHuRef
CHM1_151,392,820 - 1,445,528 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC6A3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 733809
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.